| Product name: |
KIR3.2 rabbit pAb |
| Reactivity: |
Human; Mouse; Rat |
| Alternative Names: |
G protein-activated inward rectifier potassium channel 2 (GIRK-2;BIR1;Inward rectifier K(+) channel Kir3.2;KATP-2;Potassium channel, inwardly rectifying subfamily J member 6) |
| Source: |
Rabbit |
| Dilutions: |
IHC-p 1:50-200, WB 1:500-2000 |
| Immunogen: |
Synthesized peptide derived from human KIR3.2 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
48kD |
| GeneID: |
3763 |
| Human Swiss-Prot No: |
P48051 |
| Cellular localization: |
Membrane; Multi-pass membrane protein. |
| Background: |
This gene encodes a member of the G protein-coupled inwardly-rectifying potassium channel family of inward rectifier potassium channels. This type of potassium channel allows a greater flow of potassium into the cell than out of it. These proteins modulate many physiological processes, including heart rate in cardiac cells and circuit activity in neuronal cells, through G-protein coupled receptor stimulation. Mutations in this gene are associated with Keppen-Lubinsky Syndrome, a rare condition characterized by severe developmental delay, facial dysmorphism, and intellectual disability. [provided by RefSeq, Apr 2015], |
