| Product name: |
IRF-7 (phospho-Ser477) rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
Interferon regulatory factor 7 (IRF-7) |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000;IHC-p 1:50-300 |
| Immunogen: |
Synthesized phosho peptide around human IRF-7 (Ser477) |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
55kD |
| GeneID: |
3665 |
| Human Swiss-Prot No: |
Q92985 |
| Cellular localization: |
Nucleus. Cytoplasm. The phosphorylated and active form accumulates selectively in the nucleus. |
| Background: |
IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. Multiple IRF7 transcript variants have been identified, although the functional consequences of these have not yet been established. [provided by RefSeq, Jul 2008], |
