| Product name: |
HOME2 rabbit pAb |
| Reactivity: |
Human; Mouse;Rat |
| Alternative Names: |
Homer protein homolog 2 (Homer-2) (Cupidin) |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000 |
| Immunogen: |
Synthesized peptide derived from human HOME2 AA range: 17-67 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
38kD |
| GeneID: |
9455 |
| Human Swiss-Prot No: |
Q9NSB8 |
| Cellular localization: |
Cytoplasm . Cell membrane . Cell junction, synapse, postsynaptic density. Cell junction, synapse. Cell projection, stereocilium . Postsynaptic density of neuronal cells. The stabilization and clustering of the metabotropic glutamate receptors appears to be mediated by isoform 1 and isoform 2 at the cell surface. |
| Background: |
This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. The encoded protein is a postsynaptic density scaffolding protein. Alternative splicing results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 14. [provided by RefSeq, Jun 2011], |
