| Product name: |
GGT2 rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
Gamma-glutamyltranspeptidase 2 (GGT 2) (EC 2.3.2.2) (Gamma-glutamyltransferase 2) (Glutathione hydrolase 2) (EC 3.4.19.13) [Cleaved into: Gamma-glutamyltranspeptidase 2 heavy chain; Gamma-glutamyltranspeptidase 2 light chain] |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000 |
| Immunogen: |
Synthesized peptide derived from human GGT2 AA range: 89-139 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
60kD |
| Human Swiss-Prot No: |
P36268 |
| Cellular localization: |
Cytoplasm, perinuclear region . Endoplasmic reticulum . Co-localizes with calnexin in the endoplasmic reticulum. |
| Background: |
GGT2 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied by OMIM, Oct 2008], |
