| Product name: |
FKBP1B Polyclona Antibody |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
Peptidyl-prolyl cis-trans isomerase FKBP1B (PPIase FKBP1B;EC 5.2.1.8;12.6 kDa FK506-binding protein;12.6 kDa FKBP;FKBP-12.6;FK506-binding protein 1B;FKBP-1B;Immunophilin FKBP12.6;Rotamase;h-FKBP-12) |
| Source: |
Rabbit |
| Dilutions: |
IHC-p 1:50-200, ELISA(peptide)1:5000-20000 |
| Immunogen: |
Synthesized peptide derived from human FKBP1B AA range: 35-85 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| GeneID: |
2281 |
| Human Swiss-Prot No: |
P68106 |
| Cellular localization: |
Cytoplasm . Sarcoplasmic reticulum . |
| Background: |
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms. [provided by RefSeq, Jul 2008], |
