| Product name: |
Calnexin Rabbit pAb |
| Reactivity: |
Human, Rat, Mouse |
| Alternative Names: |
CANX antibody, CNX antibody, FLJ26570 antibody, IP90 antibody, P90 antibody |
| Source: |
Rabbit |
| Dilutions: |
WB 1:1,000-2,000 IHC 1:200-500 |
| Immunogen: |
Recombinant Protein |
| Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20C. Avoidrepeatedfreeze-thawcycles. |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1mg/mL |
| Observed Band: |
75,80,90kDa |
| GeneID: |
821 |
| Human Swiss-Prot No: |
P27824 |
| Cellular localization: |
Endoplasmic reticulum membrane,Melanosome. |
| Background: |
Calnexin is a chaperone, characterized by assisting protein folding and quality control, ensuring that only properly folded and assembled proteins proceed further along the secretory pathway. Calnexin is a integral protein (that appears variously as a 90kDa, 80kDa or 75kDa band on western blotting depending on the source of the antibody) of the endoplasmic reticulum (ER). It consists of a large (50 kDa) N-terminal calcium-binding lumenal domain, a single transmembrane helix and a short (90 residues), acidic cytoplasmic tail. |
