| Product name: |
DAPK1 (Phospho-Ser308) rabbit pAb |
| Reactivity: |
Human; Mouse |
| Alternative Names: |
Death-associated protein kinase 1 (DAP kinase 1;EC 2.7.11.1) |
| Source: |
Rabbit |
| Dilutions: |
IHC-p 1:50-200, WB 1:500-2000 |
| Immunogen: |
Synthesized peptide derived from human DAPK1 (Phospho-Ser308) |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
160kD |
| GeneID: |
1612 |
| Human Swiss-Prot No: |
P53355 |
| Cellular localization: |
[Isoform 1]: Cytoplasm. Cytoplasm, cytoskeleton. Colocalizes with MAP1B in the microtubules and cortical actin fibers.; [Isoform 2]: Cytoplasm. Cytoplasm, cytoskeleton. |
| Background: |
Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013], |
