| Product name: |
CYTSA rabbit pAb |
| Reactivity: |
Human; Mouse;Rat |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000 |
| Immunogen: |
Synthesized peptide derived from human CYTSA AA range: 150-200 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Molecular Weight: |
123kD |
| GeneID: |
23384 |
| Human Swiss-Prot No: |
Q69YQ0 |
| Cellular localization: |
Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, spindle . Cell junction, gap junction . Colocalizes with acetylated alpha-tubulin, gamma-tubulin and F-actin. Also observed in a ring around gamma-tubulin containing centrioles possibly in the microtubule organizing center. |
| Background: |
This gene encodes a coiled-coil domain containing protein. The encoded protein may play a critical role in actin-cytoskeletal reorganization during facial morphogenesis. Mutations in this gene are a cause of oblique facial clefting-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A read-through transcript composed of SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and the downstream ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding. [provided by RefSeq, Jun 2013], |
