CNIH2 rabbit pAb – TO17349
TO17349
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50 µL$148.00
100 µL$248.00
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Overview

Product name: CNIH2 rabbit pAb
Reactivity: Human; Mouse;Rat
Source: Rabbit
Dilutions: WB 1:500-2000
Immunogen: Synthesized peptide derived from human CNIH2 AA range: 10-60
Storage: -20C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 18kD
GeneID: 254263
Human Swiss-Prot No: Q6PI25
Cellular localization: Endoplasmic reticulum membrane ; Multi-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell projection, dendrite . Cell projection, dendritic spine . Cell junction, synapse, postsynaptic density . Also localizes to the cell membrane of extrasynaptic sites (dendritic shafts, spines of pyramidal cells). .
Background: The protein encoded by this gene is an auxiliary subunit of the ionotropic glutamate receptor of the AMPA subtype. AMPA receptors mediate fast synaptic neurotransmission in the central nervous system. This protein has been reported to interact with the Type I AMPA receptor regulatory protein isoform gamma-8 to control assembly of hippocampal AMPA receptor complexes, thereby modulating receptor gating and pharmacology. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],