| Product name: |
EKLF (Acetyl Lys274) rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
Krueppel-like factor 1 (Erythroid krueppel-like transcription factor;EKLF) |
| Source: |
Rabbit |
| Dilutions: |
WB 1:1000-2000 ELISA 1:5000-20000 |
| Immunogen: |
Synthesized peptide derived from human EKLF (Acetyl Lys274) |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
40kD |
| GeneID: |
10661 |
| Human Swiss-Prot No: |
Q13351 |
| Cellular localization: |
Nucleus . Colocalizes with SUMO1 in nuclear speckles. . |
| Background: |
This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. [provided by RefSeq, Oct 2009], |
