| Product name: |
SRC-1 (Phospho Thr1179) rabbit pAb |
| Reactivity: |
Human;Mouse |
| Alternative Names: |
Nuclear receptor coactivator 1 (NCoA-1;EC 2.3.1.48;Class E basic helix-loop-helix protein 74;bHLHe74;Protein Hin-2;RIP160;Renal carcinoma antigen NY-REN-52;Steroid receptor coactivator 1;SRC-1) |
| Source: |
Rabbit |
| Dilutions: |
WB 1:1000-2000 ELISA 1:5000-20000 |
| Immunogen: |
Synthesized peptide derived from human SRC-1 (Phospho Thr1179) |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
158kD |
| GeneID: |
8648 |
| Human Swiss-Prot No: |
Q15788 |
| Cellular localization: |
Nucleus . |
| Background: |
The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008], |
