| Product name: |
Rac1/CDC42 (Phospho Ser71) rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
Ras-related C3 botulinum toxin substrate 1 (Cell migration-inducing gene 5 protein;Ras-like protein TC25;p21-Rac1) |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Immunogen: |
Synthesized peptide derived from human Rac1/CDC42 (Phospho Ser71) |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Molecular Weight: |
21kD |
| GeneID: |
5879 |
| Human Swiss-Prot No: |
P63000/P15153/P60763/P60953 |
| Cellular localization: |
Cell membrane ; Lipid-anchor ; Cytoplasmic side . Melanosome . Cytoplasm . Cell projection, lamellipodium . Cell projection, dendrite . Cell junction, synapse . Nucleus . Inner surface of plasma membrane possibly with attachment requiring prenylation of the C-terminal cysteine (PubMed:1903399). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). Found in the ruffled border (a late endosomal-like compartment in the plasma membrane) of bone-resorbing osteoclasts. Localizes to the lamellipodium in a SH3RF1-dependent manner (By similarity). In macrophages, cytoplasmic location increases upon CSF1 stimulation (By similarity). Activation by GTP-binding promotes nuclear localization (PubMed:12551911). . |
