| Product name: |
14-3-3-pan rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
14-3-3 protein beta/alpha (Protein 1054;Protein kinase C inhibitor protein 1;KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed] |
| Source: |
Rabbit |
| Dilutions: |
WB 1:1000-2000 ELISA 1:5000-20000 |
| Immunogen: |
Synthesized peptide derived from human 14-3-3-pan |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
30kD |
| Molecular Weight: |
27060 |
| GeneID: |
7529 |
| Human Swiss-Prot No: |
P31946/P61981/P27348/P63104/P31947 |
| Cellular localization: |
Cytoplasm . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV.; Vacuole membrane . (Microbial infection) Upon infection with Chlamydia trachomatis, this protein is associated with the pathogen-containing vacuole membrane where it colocalizes with IncG. . |
| Background: |
This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008], |
