| Product name: |
IRE1 rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
ERN1; IRE1; Serine/threonine-protein kinase/endoribonuclease IRE1; Endoplasmic reticulum-to-nucleus signaling 1; Inositol-requiring protein 1; hIRE1p; Ire1-alpha; IRE1a |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: |
Purified recombinant fragment of human IRE1 (aa282-433) expressed in E. Coli. |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Molecular Weight: |
105kD |
| GeneID: |
2081 |
| Human Swiss-Prot No: |
O75460 |
| Cellular localization: |
Endoplasmic reticulum membrane ; Single-pass type I membrane protein . |
| Background: |
The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals. [provided by RefSeq, Jul 2008], |
