| Product name: |
GABA A Receptor 3 rabbit pAb |
| Reactivity: |
Human;Rat;Mouse |
| Alternative Names: |
Gamma-aminobutyric acid receptor subunit alpha-3 (GABA(A) receptor subunit alpha-3) |
| Source: |
Rabbit |
| Dilutions: |
WB 1:1000-2000, IHC 1:100-200 |
| Immunogen: |
Synthetic Peptide of GABA A Receptor 3 AA range: 51-101 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
55kD |
| GeneID: |
2556 |
| Human Swiss-Prot No: |
P34903 |
| Cellular localization: |
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
| Background: |
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008], |