| Product name: |
GABA A Receptor 2 rabbit pAb |
| Reactivity: |
Human;Rat;Mouse |
| Alternative Names: |
Gamma-aminobutyric acid receptor subunit alpha-2 (GABA(A) receptor subunit alpha-2) |
| Source: |
Rabbit |
| Dilutions: |
WB 1:1000-2000, IHC 1:100-200 |
| Immunogen: |
Synthetic Peptide of GABA A Receptor 2 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
51kD |
| GeneID: |
282236 |
| Human Swiss-Prot No: |
P47869 |
| Cellular localization: |
Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle membrane . Cell projection, dendrite . |
| Background: |
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013], |
