| Product name: |
HoxB5 rabbit pAb |
| Reactivity: |
Human;Mouse |
| Alternative Names: |
HOXB5; HOX2A; Homeobox protein Hox-B5; Homeobox protein HHO.C10; Homeobox protein Hox-2A; Homeobox protein Hu-1 |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human HoxB5. AA range:150-199 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
29kD |
| GeneID: |
3215 |
| Human Swiss-Prot No: |
P09067 |
| Cellular localization: |
Nucleus. |
| Background: |
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue. [provided by RefSeq, Jul 2008], |
