| Product name: |
IkB Rabbit pAb |
| Reactivity: |
Human, Mouse, Rat |
| Alternative Names: |
I kappa B alpha antibody, IkB-alpha antibody, IKBA antibody, MAD3 antibody, NFKB inhibitor antibody |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-1,000 IHC 1:100-200 |
| Immunogen: |
Recombinant Protein |
| Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20C. Avoidrepeatedfreeze-thawcycles. |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1mg/mL |
| Observed Band: |
40kDa |
| GeneID: |
4792 |
| Human Swiss-Prot No: |
P25963 |
| Cellular localization: |
Cytoplasm,Nucleus |
| Background: |
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. IB phosphorylation and resulting Rel-dependent transcription are activated by a highly diverse group of extracellular signals including inflammatory cytokines, growth factors, and chemokines. |
