| Product name: |
VEGF-B rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
VEGFB; VRF; Vascular endothelial growth factor B; VEGF-B; VEGF-related factor; VRF |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human VEGFB. AA range:91-140 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
21kD |
| GeneID: |
7423 |
| Human Swiss-Prot No: |
P49765 |
| Cellular localization: |
Secreted. Secreted but remains associated to cells or to the extracellular matrix unless released by heparin. |
| Background: |
This gene encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Sep 2011], |
