| Product name: |
MIP-T3 rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
TRAF3IP1; MIPT3; TRAF3-interacting protein 1; Interleukin-13 receptor alpha 1-binding protein 1; Microtubule-interacting protein associated with TRAF3; MIP-T3 |
| Source: |
Rabbit |
| Dilutions: |
Immunohistochemistry: 1/100 – 1/300. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human MIPT3. AA range:221-270 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
78kD |
| GeneID: |
26146 |
| Human Swiss-Prot No: |
Q8TDR0 |
| Cellular localization: |
Cytoplasm, cytoskeleton . Cell projection, cilium . Cytoplasm, cytoskeleton, cilium axoneme . Cytoplasm, cytoskeleton, cilium basal body . Microtubules (PubMed:12935900). In the cilium, it is observed at the ciliary base, ciliary transition zone and ciliary tip (PubMed:26487268). . |
| Background: |
function:Play an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules.,similarity:Belongs to the TRAF3IP1 family.,subcellular location:Microtubules.,subunit:Interacts with IL13RA1. Binds to microtubules, TRAF3 and DISC1.,tissue specificity:Ubiquitous., |
