| Product name: |
SNM1B rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
DCLRE1B; SNM1B; 5′ exonuclease Apollo; DNA cross-link repair 1B protein; SNM1 homolog B; SNMIB; hSNM1B |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Immunogen: |
Synthesized peptide derived from the C-terminal region of human SNM1B. |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
60kD |
| GeneID: |
64858 |
| Human Swiss-Prot No: |
Q9H816 |
| Cellular localization: |
Chromosome, telomere. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Mainly localizes to telomeres, recruited via its interaction with TERF2. During mitosis, localizes to the centrosome. |
| Background: |
DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al., 2000 [PubMed 10848582]).[supplied by OMIM, Mar 2008], |
