| Product name: |
UBE4A rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
UBE4A; KIAA0126; Ubiquitin conjugation factor E4 A |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. IHC-p: 1:100-300 ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: |
Synthesized peptide derived from the N-terminal region of human UBE4A. |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
122kD |
| GeneID: |
9354 |
| Human Swiss-Prot No: |
Q14139 |
| Cellular localization: |
Cytoplasm . |
| Background: |
This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn’s disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011], |
