| Product name: |
KLF12 rabbit pAb |
| Reactivity: |
Human;Mouse |
| Alternative Names: |
KLF12; AP2REP; HSPC122; Krueppel-like factor 12; Transcriptional repressor AP-2rep |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: |
Synthesized peptide derived from the Internal region of human KLF12. |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
44kD |
| GeneID: |
11278 |
| Human Swiss-Prot No: |
Q9Y4X4 |
| Cellular localization: |
Nucleus. |
| Background: |
Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
