| Product name: |
HBP1 (phospho Ser402) rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
HBP1; HMG box-containing protein 1; HMG box transcription factor 1; High mobility group box transcription factor 1 |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human HBP1 around the phosphorylation site of Ser402. AA range:371-420 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
58kD |
| GeneID: |
26959 |
| Human Swiss-Prot No: |
O60381 |
| Cellular localization: |
Nucleus . |
| Background: |
function:Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5′-TTCATTCATTCA-3′. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.,similarity:Contains 1 AXH domain.,similarity:Contains 1 HMG box DNA-binding domain.,subunit:Binds the second PAH repeat of SIN3A (By similarity). Binds TCF4 and RB1., |
