| Product name: |
CD294 rabbit pAb |
| Reactivity: |
Human;Mouse |
| Alternative Names: |
PTGDR2; CRTH2; DL1R; GPR44; Prostaglandin D2 receptor 2; Chemoattractant receptor-homologous molecule expressed on Th2 cells; G-protein coupled receptor 44; CD294 |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the Internal region of human PTGDR2. AA range:161-210 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
43kD |
| GeneID: |
11251 |
| Human Swiss-Prot No: |
Q9Y5Y4 |
| Cellular localization: |
Cell membrane ; Multi-pass membrane protein . Internalized receptors colocalized with RAB11A. . |
| Background: |
This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3′ UTR of this gene have been associated with asthma susceptibility.[provided by RefSeq, Mar 2011], |
