| Product name: |
IGF-I rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
IBP1; IGF-IA; IGF1A; IGFI; insulin-like growth factor 1; insulin-like growth factor IA; mechano growth factor; MGF; somatomedin C |
| Source: |
Rabbit |
| Dilutions: |
Immunohistochemistry: 1/100 – 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human IGF-I. AA range:100-149 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Molecular Weight: |
17-22kD |
| GeneID: |
3479 |
| Human Swiss-Prot No: |
P01343/P05019 |
| Cellular localization: |
extracellular region,extracellular space,plasma membrane,insulin-like growth factor binding protein complex,platelet alpha granule lumen,alphav-beta3 integrin-IGF-1-IGF1R complex,insulin-like growth factor ternary complex,exocytic vesicle, |
| Background: |
The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015], |
