| Product name: |
IRAK-1 (phospho Thr100) rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
IRAK1; IRAK; Interleukin-1 receptor-associated kinase 1; IRAK-1 |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human IRAK1 around the phosphorylation site of Thr100. AA range:66-115 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
77kD |
| GeneID: |
3654 |
| Human Swiss-Prot No: |
P51617 |
| Cellular localization: |
Cytoplasm . Nucleus . Lipid droplet . Translocates to the nucleus when sumoylated. RSAD2/viperin recruits it to the lipid droplet (By similarity). . |
| Background: |
This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
