| Product name: |
COL4A5 rabbit pAb |
| Reactivity: |
Human;Mouse |
| Alternative Names: |
COL4A5; Collagen alpha-5(IV) chain |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000 Immunohistochemistry: 1/100 – 1/300. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human Collagen IV alpha5. AA range:21-70 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
160kD |
| GeneID: |
1287 |
| Human Swiss-Prot No: |
P29400 |
| Cellular localization: |
Secreted, extracellular space, extracellular matrix, basement membrane. |
| Background: |
This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Mutations in this gene are associated with X-linked Alport syndrome, also known as hereditary nephritis. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Aug 2010], |
