| Product name: |
ARHGEF10 rabbit pAb |
| Reactivity: |
Human;Monkey |
| Alternative Names: |
ARHGEF10; KIAA0294; Rho guanine nucleotide exchange factor 10 |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human ARHGEF10. AA range:339-388 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
152kD |
| GeneID: |
9639 |
| Human Swiss-Prot No: |
O15013 |
| Cellular localization: |
centrosome,cytosol, |
| Background: |
This gene encodes a Rho guanine nucleotide exchange factor (GEF). Rho GEFs regulate the activity of small Rho GTPases by stimulating the exchange of guanine diphosphate (GDP) for guanine triphosphate (GTP) and may play a role in neural morphogenesis. Mutations in this gene are associated with slowed nerve conduction velocity (SNCV). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015], |
