| Product name: |
eIF4B (phospho Ser422) rabbit pAb |
| Reactivity: |
Human;Mouse |
| Alternative Names: |
EIF4B; Eukaryotic translation initiation factor 4B; eIF-4B |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human eIF4B around the phosphorylation site of Ser422. AA range:388-437 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
80kD |
| GeneID: |
3716 |
| Human Swiss-Prot No: |
P23588 |
| Cellular localization: |
cytosol,polysome,eukaryotic translation initiation factor 4F complex,dendrite,neuronal cell body, |
| Background: |
function:Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5′-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Self-associates and interacts with EIF3 p170 subunit., |
