| Product name: |
Eme1 rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
EME1; MMS4; Crossover junction endonuclease EME1; MMS4 homolog; hMMS4 |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen: |
Synthesized peptide derived from Eme1 . at AA range: 250-330 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
65kD |
| GeneID: |
146956 |
| Human Swiss-Prot No: |
Q96AY2 |
| Cellular localization: |
Nucleus, nucleolus . Recruited to regions of DNA damage in S-phase cells. |
| Background: |
This gene encodes a protein that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3′-flap structures and aberrant replication fork structures. This protein may be involved in repairing DNA damage and in maintaining genomic stability. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009], |
