| Product name: |
PP4R2 rabbit pAb |
| Reactivity: |
Human;Monkey |
| Alternative Names: |
PPP4R2; SBBI57; Serine/threonine-protein phosphatase 4 regulatory subunit 2 |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human PPP4R2. AA range:171-220 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
50kD |
| GeneID: |
151987 |
| Human Swiss-Prot No: |
Q9NY27 |
| Cellular localization: |
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Ionizing radiation induces relocalization to nuclear foci and colocalization with RPA2. |
| Background: |
The protein encoded by this gene is a regulatory subunit of the serine/threonine-protein phosphatase 4 complex. In addition to being required for efficient DNA double strand break repair, this complex plays a role in organization of microtubules at centrosomes and processing of spliceosomal snRNPs. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015], |
