| Product name: |
NAC3 rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: |
Synthesized peptide derived from human protein . at AA range: 530-610 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
101kD |
| GeneID: |
6547 |
| Human Swiss-Prot No: |
P57103 |
| Cellular localization: |
Cell membrane ; Multi-pass membrane protein . Perikaryon . Cell projection, dendrite . Cell projection, dendritic spine . Cell membrane, sarcolemma . Cytoplasm, sarcoplasm . Cell junction . Mitochondrion outer membrane ; Multi-pass membrane protein . Cytoplasm, perinuclear region . Endoplasmic reticulum membrane ; Multi-pass membrane protein . Detected at neuromuscular junctions. . |
| Background: |
This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described. [provided by RefSeq, Aug 2013], |
