| Product name: |
MMP-8 rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
MMP8; CLG1; Neutrophil collagenase; Matrix metalloproteinase-8; MMP-8; PMNL collagenase; PMNL-CL |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human MMP-8. AA range:418-467 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
55kD |
| GeneID: |
4317 |
| Human Swiss-Prot No: |
P22894 |
| Cellular localization: |
Cytoplasmic granule. Secreted, extracellular space, extracellular matrix . Stored in intracellular granules. |
| Background: |
matrix metallopeptidase 8(MMP8) Homo sapiens This gene encodes a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N-termini. This protein functions in the degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015], |
