| Product name: |
Peroxin 1 rabbit pAb |
| Reactivity: |
Human;Mouse |
| Alternative Names: |
PEX1; Peroxisome biogenesis factor 1; Peroxin-1; Peroxisome biogenesis disorder protein 1 |
| Source: |
Rabbit |
| Dilutions: |
Immunohistochemistry: 1/100 – 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human PEX1. AA range:1234-1283 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Molecular Weight: |
143kD |
| GeneID: |
5189 |
| Human Swiss-Prot No: |
O43933 |
| Cellular localization: |
Cytoplasm. Peroxisome membrane. Associated with peroxisomal membranes. |
| Background: |
This gene encodes a member of the AAA ATPase family, a large group of ATPases associated with diverse cellular activities. This protein is cytoplasmic but is often anchored to a peroxisomal membrane where it forms a heteromeric complex and plays a role in the import of proteins into peroxisomes and peroxisome biogenesis. Mutations in this gene have been associated with complementation group 1 peroxisomal disorders such as neonatal adrenoleukodystrophy, infantile Refsum disease, and Zellweger syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013], |
