| Product name: |
TEM7 rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
PLXDC1; TEM3; TEM7; Plexin domain-containing protein 1; Tumor endothelial marker 3; Tumor endothelial marker 7 |
| Source: |
Rabbit |
| Dilutions: |
Immunohistochemistry: 1/100 – 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human PLXDC1. AA range:71-120 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Molecular Weight: |
56kD |
| GeneID: |
57125 |
| Human Swiss-Prot No: |
Q8IUK5 |
| Cellular localization: |
[Isoform 1]: Cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Localized predominantly at the tight junctions of vascular endothelial cells and to a lesser extent at the luminal surface of vascular endothelial cells.; [Isoform 2]: Secreted .; [Isoform 3]: Secreted .; [Isoform 4]: Cytoplasm . |
| Background: |
PTM:N-glycosylated.,similarity:Belongs to the plexin family.,subunit:May interact with cortactin.,tissue specificity:Detected in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. Not detectable in endothelial cells from normal tissue., |
