| Product name: |
ARHGAP23 rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
ARHGAP23; KIAA1501; Rho GTPase-activating protein 23; Rho-type GTPase-activating protein 23 |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000 Immunohistochemistry: 1/100 – 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: |
Synthesized peptide derived from ARHGAP23 . at AA range: 470-550 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Molecular Weight: |
162kD |
| GeneID: |
57636 |
| Human Swiss-Prot No: |
Q9P227 |
| Cellular localization: |
cytosol,extracellular exosome, |
| Background: |
The RHO (see ARHA; MIM 165390) family of small GTPases are involved in signal transduction through transmembrane receptors, and they are inactive in the GDP-bound form and active in the GTP-bound form. GTPase-activating proteins, such as ARHGAP23, inactivate RHO family proteins by stimulating their hydrolysis of GTP (Katoh and Katoh, 2004 [PubMed 15254754]).[supplied by OMIM, Mar 2008], |
