| Product name: |
TGF RI (phospho Ser165) rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
TGFBR1; ALK5; SKR4; TGF-beta receptor type-1; TGFR-1; Activin A receptor type II-like protein kinase of 53kD; Activin receptor-like kinase 5; ALK-5; ALK5; Serine/threonine-protein kinase receptor R4; SKR4; TGF-beta type I receptor; Transfor |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000, IF 1:50-300, IHC 1:50-300 |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human TGF beta Receptor I around the phosphorylation site of Ser165. AA range:131-180 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Molecular Weight: |
56kD |
| GeneID: |
7046 |
| Human Swiss-Prot No: |
P36897 |
| Cellular localization: |
Cell membrane ; Single-pass type I membrane protein . Cell junction, tight junction . Cell surface . Membrane raft . |
| Background: |
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008], |
