| Product name: |
FGF-23 rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
FGF23; HYPF; Fibroblast growth factor 23; FGF-23; Phosphatonin; Tumor-derived hypophosphatemia-inducing factor |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human FGF23. AA range:151-200 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
27kD |
| GeneID: |
8074 |
| Human Swiss-Prot No: |
Q9GZV9 |
| Cellular localization: |
Secreted . Secretion is dependent on O-glycosylation. |
| Background: |
This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC). [provided by RefSeq, Feb 2013], |
