| Product name: |
EMR3 rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
EMR3; EGF-like module-containing mucin-like hormone receptor-like 3; EGF-like module receptor 3 |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. Immunofluorescence: 1/200 – 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human EMR3. AA range:603-652 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
70kD |
| GeneID: |
84658 |
| Human Swiss-Prot No: |
Q9BY15 |
| Cellular localization: |
Cell membrane; Multi-pass membrane protein .; [Isoform 3]: Secreted. |
| Background: |
This gene encodes a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2014], |
