COX5A; Cytochrome c oxidase subunit 5A; mitochondrial; Cytochrome c oxidase polypeptide Va
Source:
Rabbit
Dilutions:
Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen:
Synthesized peptide derived from COX5a . at AA range: 40-120
Storage:
-20C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Observed Band:
17kD
GeneID:
9377
Human Swiss-Prot No:
P20674
Cellular localization:
Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side .
Background:
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer of proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Va of the human mitochondrial respiratory chain enzyme. A pseudogene COX5AP1 has been found in chromosome 14q22. [provided by RefSeq, Jul 2008],