MPP1 rabbit pAb – TO8068
TO8068
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50 µL$148.00
100 µL$248.00
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Overview

Product name: MPP1 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: KIF20B; KRMP1; MPHOSPH1; Kinesin-like protein KIF20B; Cancer/testis antigen 90; CT90; Kinesin-related motor interacting with PIN1; M-phase phosphoprotein 1; MPP1
Source: Rabbit
Dilutions: IF/ICC 1:50-300; ELISA 1:2000-20000; IHC-p 1:50-200
Immunogen: The antiserum was produced against synthesized peptide derived from human KIF20B. AA range:1771-1820
Storage: -20C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 210kD
GeneID: 9585
Human Swiss-Prot No: Q96Q89
Cellular localization: Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Nucleus, nucleolus . Nucleus, nucleoplasm . Cytoplasm, cytoskeleton, spindle . Cytoplasm, cytoskeleton, spindle pole . Midbody . Cell projection, axon . Cell projection, growth cone . Localizes mainly in the nucleus during interphase although it is also detected in the cytoplasm without clear association with microtubules (PubMed:12740395). Localized to the central spindle during cytokinetic furrowing and with the midbody during abscission (PubMed:12740395, PubMed:17409436). A 2-3 fold expression increase is seen as cells progress from G1 to G2/M phase (PubMed:12740395). During prophase and metaphase it is found throughout the cytoplasm and at anaphase accumulates at the midplan of the cell and forms a distinct
Background: KIF20B (Kinesin Family Member 20B) is a Protein Coding gene. Among its related pathways areGolgi-to-ER retrograde transportandFactors involved in megakaryocyte development and platelet production. GO annotations related to this gene includeATPase activityandmicrotubule motor activity. An important paralog of this gene isKIF23.