| Product name: |
MAGI-2 rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
MAGI2; ACVRINP1; AIP1; KIAA0705; Membrane-associated guanylate kinase; WW and PDZ domain-containing protein 2; Atrophin-1-interacting protein 1; AIP-1; Atrophin-1-interacting protein A; Membrane-associated guanylate kinase inverted 2; MAGI- |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. Immunohistochemistry: 1/100 – 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human MAGI2. AA range:221-270 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
156kD |
| GeneID: |
9863 |
| Human Swiss-Prot No: |
Q86UL8 |
| Cellular localization: |
Cytoplasm . Late endosome . Cell junction, synapse, synaptosome . Cell membrane ; Peripheral membrane protein . Localized diffusely in the cytoplasm before nerve growth factor (NGF) stimulation. Recruited to late endosomes after NGF stimulation. Membrane-associated in synaptosomes (By similarity). . |
| Background: |
The protein encoded by this gene interacts with atrophin-1. Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains, a guanylate kinase-like domain, and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family. [provided by RefSeq, Jul 2008], |
