| Product name: |
CD249 rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
ENPEP; Glutamyl aminopeptidase; EAP; Aminopeptidase A; AP-A; Differentiation antigen gp160; CD249 |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the Internal region of human ENPEP. AA range:671-720 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
110kD |
| GeneID: |
2028 |
| Human Swiss-Prot No: |
Q07075 |
| Cellular localization: |
Cell membrane ; Single-pass type II membrane protein. |
| Background: |
catalytic activity:Release of N-terminal glutamate (and to a lesser extent aspartate) from a peptide.,cofactor:Binds 1 zinc ion per subunit.,function:Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells.,similarity:Belongs to the peptidase M1 family.,subunit:Homodimer; disulfide-linked.,tissue specificity:Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues., |
