| Product name: |
Calretinin rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
Calretinin (CR;29 kDa calbindin) |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 – 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: |
Synthesized peptide derived from calbindin 2 at AA range: 191-240 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
32kD |
| GeneID: |
794 |
| Human Swiss-Prot No: |
P22676 |
| Cellular localization: |
nucleus,cytoplasm,cytosol,gap junction,neuron projection,terminal bouton,synapse, |
| Background: |
This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010], |
