| Product name: |
Acetyl-EPAS-1 (K385) rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
endothelial PAS domain protein 1 |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000, ELISA 1:10000-20000 |
| Immunogen: |
Synthesized acetyl-peptide of Acetyl-EPAS-1 (K385) |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
120kD |
| GeneID: |
2034 |
| Human Swiss-Prot No: |
Q99814 |
| Cellular localization: |
Nucleus . Nucleus speckle . Colocalizes with HIF3A in the nucleus and speckles. . |
| Background: |
endothelial PAS domain protein 1(EPAS1) Homo sapiens This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009], |
