| Product name: |
E2F-3 (Acetyl Lys168) rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
E2F3 KIAA0075 |
| Source: |
Rabbit |
| Dilutions: |
WB: 1:500-10000 ELISA: 1:10000 |
| Immunogen: |
Synthesized acetyl-peptide from human protein at AA range: 130-200 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
50kD |
| GeneID: |
1871 |
| Human Swiss-Prot No: |
O00716 |
| Cellular localization: |
Nucleus. |
| Background: |
This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle. Altered copy number and activity of this gene have been observed in a number of human cancers. There are pseudogenes for this gene on chromosomes 2 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013], |
