| Product name: |
VPS35 rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
Vacuolar protein sorting-associated protein 35 (hVPS35) (Maternal-embryonic 3) (Vesicle protein sorting 35) |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000, ELISA 1:10000-20000 |
| Immunogen: |
Synthesized peptide derived from VPS35 at AA range: 511-560 |
| Storage: |
-20C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
92kD |
| GeneID: |
55737 |
| Human Swiss-Prot No: |
Q96QK1 |
| Cellular localization: |
Cytoplasm. Membrane; Peripheral membrane protein. Endosome . Early endosome . Late endosome . Localizes to tubular profiles adjacent to endosomes. . |
| Background: |
This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. [provided by RefSeq, Jul 2008], |
