Cytokeratin 14/17 rabbit pAb – TO8537
TO8537
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50 µL$148.00
100 µL$248.00
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Overview

Product name: Cytokeratin 14/17 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: KRT14
Source: Rabbit
Dilutions: WB 1:500-2000, ELISA 1:10000-20000
Immunogen: Synthetic peptide from human protein at AA range: 261-310
Storage: -20C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 52kD
GeneID: 3861
Human Swiss-Prot No: P02533/Q04695
Cellular localization: Cytoplasm. Nucleus. Expressed in both as a filamentous pattern.
Background: This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11. [provided by RefSeq, Jul 2008],