IL-31 rabbit pAb – TO8589
TO8589
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50 µL$148.00
100 µL$248.00
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Overview

Product name: IL-31 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: Interleukin-31 (IL-31)
Source: Rabbit
Dilutions: WB 1:500-2000, IHC-p 1:50-200 ELISA 1:10000-20000
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human IL31. AA range:21-70
Storage: -20C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 65kD
GeneID: 386653
Human Swiss-Prot No: Q6EBC2
Cellular localization: Secreted .
Background: IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM, Mar 2008],